Evaluation of interferon-stimulated gene 15 (ISG15) expression in blood neutrophils in beef cattle poisoned by Senecio spp.

ABSTRACT: This study aimed to assess liver damage and interferon-stimulated gene 15 (ISG15) blood expression as a consequence of embryonic signaling on maternal recognition pregnancy in beef cattle presenting natural ingestion Senecio spp. Epidemiological aspects, the presence plant, associated gamma glutamyl transferase (GGT) activity can be used poisoning diagnosis. Maternal period occurs when embryo secretes interferon tau (IFNT) signal its mother eventually extend corpus luteum (CL) lifespan. In our study, was determined by concentration serum GGT, cytological histopathological examinations. Reproductive status evaluated progesterone, CL diameter ISG15 mRNA Day 19 following fixed-time artificial insemination (FTAI). Cows were categorized into two groups based GGT: Group 1 (GGT<30U/L) 2 (GGT>31U/L). No difference body condition scores observed. All cows presented cytology exams. from had higher rate, larger greater progesterone. Interestingly, no between Groups 2, even status. These findings suggest loss beyond 19. It suggests late mortality may insufficiency. conclusion, injury and/or GGT does not alter neutrophils, however lower (<30U/L) increased Therefore, allow us screen foresee successful cattle.